SMU-V18

• Description :

  SMU-V18 is a vesicular stomatitis virus (VSV) inhibitor, with an EC50 of 6.2 μM. SMU-V18 inhibits VSV-GFP fluorescence intensity, viral mRNA/protein expression, and progeny virus replication. SMU-V18 interferes with early viral infection stages, also effective against wild-type VSV (VSV-WT) . SMU-V18 inhibits VSV-GFP in mouse tissues and prolongs survival. SMU-V18 can be used for the study of vesicular stomatitis virus (VSV) infection[1].

• UNSPSC :

  12352005

• Target :

  VSV

• Related Pathways :

  Anti-infection

• Field of Research :

  Infection

• Smiles :

  O=C(C1=NC(C2=CC=C3OCCOC3=C2)=NC=C1)NC4=CC(F)=C(F)C(F)=C4

• Molecular Formula :

  C19H12F3N3O3

• Molecular Weight :

  387.31

• References & Citations :

  [1]Ren Z, et al. Design, synthesis, and biological evaluation of novel pyrimidine/pyridine derivatives for Vesicular Stomatitis Virus (VSV) infection. Eur J Med Chem. 2025 Dec 5;299:118051.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported