SMU-L11

CAT: 0931-MF-0116463-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0116463-01Size:10 mg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
NF-?B|||MAPK|||TLR
Related Pathways
Immunology/Inflammation|||NF-?B|||MAPK
Bioactivity
SMU-L11 is a specific TLR7 agonist (EC50=0.024 ?M) that recruits the MyD88 adaptor protein, activating downstream NF-?B and MAPK signaling pathways. In mouse models, SMU-L11 significantly enhances immune cell activation and boosts CD4+ T and CD8+ T cell proliferation, leading to direct tumor cell destruction and inhibition of tumor growth. This compound has applications in cancer research and potential in studying immune system disorders.
Molecular Formula
C19H24N4O
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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