SMU-L11

• Target :

  NF-?B|||MAPK|||TLR

• Related Pathways :

  Immunology/Inflammation|||NF-?B|||MAPK

• Bioactivity :

  SMU-L11 is a specific TLR7 agonist (EC50=0.024 ?M) that recruits the MyD88 adaptor protein, activating downstream NF-?B and MAPK signaling pathways. In mouse models, SMU-L11 significantly enhances immune cell activation and boosts CD4+ T and CD8+ T cell proliferation, leading to direct tumor cell destruction and inhibition of tumor growth. This compound has applications in cancer research and potential in studying immune system disorders.

• Molecular Formula :

  C19H24N4O

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C