Products for Research Use Only
RegisterLogin

Riboswit-modulator-1

CAT: 0804-HY-175761Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-175761Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Riboswit-modulator-1 (Compound A1), a covalent RNA ligand, is a bacterial Flavin mononucleotide (FMN) riboswitch modulator. Riboswit-modulator-1 modifies unpaired guanine residues (G11 and G62) proximal to the FMN-binding site through a proximity-driven mechanism, and interferes with its conformational transitions. Riboswit-modulator-1 acts as a negative antagonist by eliciting the opposite effect of the natural effector molecule[1].
UNSPSC
12352005
Target
Bacterial
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
CC1=CC2=C(N=C(C(N3)=O)C(N2CCNC4=CC=C(C(C(O)O)=O)C=C4)=NC3=O)C=C1C
Molecular Formula
C22H21N5O5
Molecular Weight
435.43
References & Citations
[1]Li C, et al. Structure-Guided Design of a Bioactive Covalent Small Molecule Targeting a Riboswitch. bioRxiv [Preprint]. 2025 Aug 2:2025.08.01.668122.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-164311GPR17 modulator-1
HY-111996-01Kv3 modulator 1
HY-148617ALDH2 modulator 1
HY-153690Progranulin modulator-1
HY-135671AhR modulator-1
HY-148878Ras modulator-1
HY-175597ClpP modulator-1
HY-169913ERAP1 modulator-1
HY-159742-01GP130 modulator-1
HY-169288α-Synuclein modulator 1

Alternative Products

CatalogName
GTR19272936-01Riboswit-modulator-1
ASB50675-01GPR120 modulator 1
T212378-01Kinase modulator-1
T204644-01MOR modulator-1
T61645-01Utrophin modulator 1
T9970-01MGluR3 modulator-1
T89304-01GPR17 modulator-1
T86740-01IRAK4 modulator-1
326098NODAL modulator 1
T10273-01AhR modulator-1

Popular Products