BMS-025

• Description :

  BMS-025 is a orthosteric STING agonist. BMS-025 can induces chemical shift of STING M271 residue, further activating STING IFN signaling. BMS-025 can be used for monogenic autoinflammatory disease like SAVI disease research[1].

• UNSPSC :

  12352005

• Target :

  STING

• Related Pathways :

  Immunology/Inflammation

• Field of Research :

  Inflammation/Immunology

• Smiles :

  NC1=C2N=CN(C2=NC=N1)[C@@H]3C[C@@H]4OP(S)(OC[C@H]5O[C@H]([C@@H]([C@@H]5O)OP(S)(OC[C@H]43)=O)N6C=NC7=C6N=C8NC=CN8C7=O)=O

• Molecular Formula :

  C22H24N10O9P2S2

• Molecular Weight :

  698.57

• References & Citations :

  [1]Xie T, et al. Orthosteric STING inhibition elucidates molecular correction of SAVI STING. Nat Commun. 2025 Jul 1;16 (1) :5695.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported