ACHM-025

• Description:

  ACHM-025 is a prodrug, which is selectively activated by AKR1C3 to a nitrogen mustard DNA alkylating agent. ACHM-025 can be used for the research of cancer, such as leukemia[1].

• UNSPSC:

  12352005

• Target:

  Others

• Related Pathways:

  Others

• Field of Research:

  Cancer

• Purity:

  98.06

• Smiles:

  O=S (C1=CC ([N+] ([O-]) =O) =CC=C1N (CCOS (=O) (C) =O) CCOS (=O) (C) =O) (N2CCN (CC2) C) =O

• Molecular Formula:

  C17H28N4O10S3

• Molecular Weight:

  544.62

• References & Citations:

  [1]Toscan CE, et al. The third generation AKR1C3-activated prodrug, ACHM-025, eradicates disease in preclinical models of aggressive T-cell acute lymphoblastic leukemia. Blood Cancer J. 2024 Nov 6;14 (1) :192.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light, stored under nitrogen)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  2377718-85-7