ACHM-025

• Description :

  ACHM-025 is a prodrug, which is selectively activated by AKR1C3 to a nitrogen mustard DNA alkylating agent. ACHM-025 can be used for the research of cancer, such as leukemia[1].

• UNSPSC :

  12352005

• Target :

  Others

• Related Pathways :

  Others

• Field of Research :

  Cancer

• Purity :

  98.06

• Smiles :

  O=S(C1=CC([N+]([O-])=O)=CC=C1N(CCOS(=O)(C)=O)CCOS(=O)(C)=O)(N2CCN(CC2)C)=O

• Molecular Formula :

  C17H28N4O10S3

• Molecular Weight :

  544.62

• References & Citations :

  [1]Toscan CE, et al. The third generation AKR1C3-activated prodrug, ACHM-025, eradicates disease in preclinical models of aggressive T-cell acute lymphoblastic leukemia. Blood Cancer J. 2024 Nov 6;14 (1) :192.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, protect from light, stored under nitrogen)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [2377718-85-7]