ACHM-025

CAT: 0804-HY-172314-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-172314-01Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ACHM-025 is a prodrug, which is selectively activated by AKR1C3 to a nitrogen mustard DNA alkylating agent. ACHM-025 can be used for the research of cancer, such as leukemia[1].
CAS Number
[2377718-85-7]
UNSPSC
12352005
Target
Others
Related Pathways
Others
Field of Research
Cancer
Purity
98.06
Smiles
O=S(C1=CC([N+]([O-])=O)=CC=C1N(CCOS(=O)(C)=O)CCOS(=O)(C)=O)(N2CCN(CC2)C)=O
Molecular Formula
C17H28N4O10S3
Molecular Weight
544.62
References & Citations
[1]Toscan CE, et al. The third generation AKR1C3-activated prodrug, ACHM-025, eradicates disease in preclinical models of aggressive T-cell acute lymphoblastic leukemia. Blood Cancer J. 2024 Nov 6;14 (1) :192.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported