L662,025

• UNSPSC Description:

  L662,025 is a specific, photolabile and irreversible Platelet-activating factor (PAF-receptor) antagonist, with IC50 values of 5.6 μM (platelet aggregation) and 1 μM (receptor binding), respectively[1].

• Target Antigen:

  Platelet-activating Factor Receptor (PAFR)

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein

• Field of Research:

  Metabolic Disease; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/l662-025.html

• Smiles:

  COC1=C(OC)C(OC)=CC([C@H]2CC[C@H](C3=CC(OC)=C(OCC=C)C(N=[N+]=[N-])=C3)O2)=C1

• Molecular Weight:

  441.48

• References & Citations:

  [1]I M Hussaini, et al. A SPECIFIC, PHOTOLABILE AND ANTAGONIST(L662,025)OF THE PAFRECEPTOR. Biochem Biophys Res Commun. 1989 May 30;161(1):23-30.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  122328-38-5