L662,025

• Description :

  L662,025 is a specific, photolabile and irreversible Platelet-activating factor (PAF-receptor) antagonist, with IC50 values of 5.6 μM (platelet aggregation) and 1 μM (receptor binding), respectively[1].

• CAS Number :

  [122328-38-5]

• UNSPSC :

  12352005

• Target :

  Platelet-activating Factor Receptor (PAFR)

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein

• Field of Research :

  Metabolic Disease; Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/l662-025.html

• Smiles :

  COC1=C(OC)C(OC)=CC([C@H]2CC[C@H](C3=CC(OC)=C(OCC=C)C(N=[N+]=[N-])=C3)O2)=C1

• Molecular Formula :

  C23H27N3O6

• Molecular Weight :

  441.48

• References & Citations :

  [1]I M Hussaini, et al. A SPECIFIC, PHOTOLABILE AND ANTAGONIST (L662,025) OF THE PAFRECEPTOR. Biochem Biophys Res Commun. 1989 May 30;161 (1) :23-30.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported