SP-C01

• Description:

  SP-C01 is an orally active soluble epoxide hydrolase (sEH) inhibitor and partial PPARγ agonist. SP-C01 can inhibit Ser273 phosphorylation[1].

• UNSPSC:

  12352005

• Target:

  Epoxide Hydrolase; PPAR

• Related Pathways:

  Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

• Field of Research:

  Metabolic Disease; Inflammation/Immunology

• Smiles:

  CC(OC1=CC=C(O[C@H]2CC[C@@H](CC2)NC(NC3=CC=C(C(F)=C3)OC(F)(F)F)=O)C=C1)=O

• Molecular Formula:

  C22H22F4N2O5

• Molecular Weight:

  470.41

• References & Citations:

  [1]Cao R, et al. Structure-Based Design and Optimization Lead to the Identification of a Novel Potent sEH Inhibitor with PPARγ Partial Agonist Activity against Inflammatory and Metabolic-Related Diseases. J Med Chem. 2025 Apr 24;68 (8) :8729-8767.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [2982533-42-4]