SP-C01

• Description :

  SP-C01 is an orally active soluble epoxide hydrolase (sEH) inhibitor and partial PPARγ agonist. SP-C01 can inhibit Ser273 phosphorylation[1].

• CAS Number :

  [2982533-42-4]

• UNSPSC :

  12352005

• Target :

  Epoxide Hydrolase; PPAR

• Related Pathways :

  Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

• Field of Research :

  Metabolic Disease; Inflammation/Immunology

• Smiles :

  CC(OC1=CC=C(O[C@H]2CC[C@@H](CC2)NC(NC3=CC=C(C(F)=C3)OC(F)(F)F)=O)C=C1)=O

• Molecular Formula :

  C22H22F4N2O5

• Molecular Weight :

  470.41

• References & Citations :

  [1]Cao R, et al. Structure-Based Design and Optimization Lead to the Identification of a Novel Potent sEH Inhibitor with PPARγ Partial Agonist Activity against Inflammatory and Metabolic-Related Diseases. J Med Chem. 2025 Apr 24;68 (8) :8729-8767.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported