Vin-C01

• Description :

  Vin-C01 is a potent pancreatic β-cells protective agent with an EC50 of 0.22 μM. Vin-C01 effectively promotes β-cell survival and protects β-cells from STZ (HY-13753) -induced apoptosis. Vin-C01 can be used for type 2 diabetes mellitus research[1].

• UNSPSC :

  12352005

• Target :

  Apoptosis

• Type :

  Reference compound

• Related Pathways :

  Apoptosis

• Applications :

  Neuroscience-Neurodegeneration

• Field of Research :

  Cardiovascular Disease

• Assay Protocol :

  https://www.medchemexpress.com/vin-c01.html

• Solubility :

  10 mM in DMSO

• Smiles :

  [H][C@]12C3=C4CCN1CCC[C@]2(C=C(N3C5=CC=CC=C54)CO)CC

• Molecular Formula :

  C20H24N2O

• Molecular Weight :

  308.42

• References & Citations :

  [1]Wang J, et al. Design, synthesis and biological evaluation of vincamine derivatives as potential pancreatic β-cells protective agents for the treatment of type 2 diabetes mellitus. Eur J Med Chem. 2020 Feb 15;188:111976.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [23173-26-4]