T16A(inh)-C01

• UNSPSC Description:

  T16A(inh)-C01 is an inhibitor of TMEM16A (ANO1). T16A(inh)-C01 blocks chloride channel mediated by ANO1 with an IC50 of 8.4 μM, without interfering with calcium signaling[1].

• Target Antigen:

  Chloride Channel

• Type:

  Reference compound

• Related Pathways:

  Membrane Transporter/Ion Channel

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/t16a-inh-c01.html

• Purity:

  90

• Solubility:

  DMSO : ≥ 100 mg/mL

• Smiles:

  O=C(OCC)C1=C(OC2=CC=C(C=C12)O)COC3=CC=CC=C3

• Molecular Weight:

  312.321

• References & Citations:

  [1]Namkung W, et al. TMEM16A inhibitors reveal TMEM16A as a minor component of calcium-activated chloride channel conductance in airway and intestinal epithelial cells. J Biol Chem. 2011 Jan 21. 286(3):2365-74.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  171506-87-9