Sp-cGMPS

• Description :

  Sp-cGMPS is an activator of cGMP-dependent protein kinases (PKGs) . Sp-cGMPS can be used in cardiovascular disease-related research[1].

• UNSPSC :

  12352005

• Target :

  PKG

• Type :

  Reference compound

• Related Pathways :

  Stem Cell/Wnt

• Field of Research :

  Cardiovascular Disease

• Assay Protocol :

  https://www.medchemexpress.com/sp-cgmps.html

• Smiles :

  O=C1C2=C(NC(N)=N1)N([C@@](O[C@@](CO3)([H])[C@@]4([H])O[P@]3(S)=O)([H])[C@@H]4O)C=N2

• Molecular Formula :

  C10H12N5O6PS

• Molecular Weight :

  361.27

• References & Citations :

  [1]Archer SL, et al. Nitric oxide and cGMP cause vasorelaxation by activation of a charybdotoxin-sensitive K channel by cGMP-dependent protein kinase. Proc Natl Acad Sci U S A. 1994 Aug 2;91 (16) :7583-7. |[2]Butt E, et al. Inhibition of cyclic GMP-dependent protein kinase-mediated effects by (Rp) -8-bromo-PET-cyclic GMPS. Br J Pharmacol. 1995 Dec;116 (8) :3110-6.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [86562-10-9]