SP-471

• UNSPSC Description:

  SP-471 is a potent dengue virus (DENV) protease inhibitor with IC50 value of 18 μM. SP-471 inhibits both intermolecular and intramolecular protease processes of DENV[1].

• Target Antigen:

  Dengue virus; Flavivirus; Virus Protease

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-anti-virus

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/sp-471.html

• Solubility:

  10 mM in DMSO

• Smiles:

  N=C(C1=CC=CC(C2=CC=C3C(C4=C(N3CC5=CC=CC(Br)=C5)C=CC(C6=CC=CC(C(N)=N)=C6)=C4)=C2)=C1)N

• Molecular Weight:

  572.50

• References & Citations:

  [1]Swarbrick C, Zogali V, Chan KWK, et al. Amidoxime prodrugs convert to potent cell-active multimodal inhibitors of the dengue virus protease. Eur J Med Chem. 2021;224:113695.

• Shipping Conditions:

  Room Temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2768010-39-3