Antimalarial agent 49

• Description:

  Antimalarial agent 49 is an orally active antimalarial compound. Antimalarial agent 49 inhibits growth of Pf3D7 and PfK1 strains (IC50: 0.84 μM and 0.4 μM respectively) . Antimalarial agent 49 has antimalarial activity and inhibits the development of P. berghei liver stages. Antimalarial agent 49 can be used in the study of Plasmodium infection[1].

• UNSPSC:

  12352005

• Target:

  Parasite

• Related Pathways:

  Anti-infection

• Field of Research:

  Infection

• Smiles:

  O=C(C1=CC2=C(C(C3=CC=C(F)C=C3)=N1)NC4=C2C=CC=C4)NCC5=CN(C6=CC=CC(C(F)(F)F)=C6)N=N5

• Molecular Formula:

  C28H18F4N6O

• Molecular Weight:

  530.48

• References & Citations:

  [1]Kushawaha AK, et al. Design, synthesis and evaluation of novel carboline-triazole hybrids as promising antimalarial agents. Eur J Med Chem. 2025 Jun 5;290:117514.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported