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PSB 0777 ammonium hydrate

CAT: 0931-T78084-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T78084-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Adenosine Receptor
Related Pathways
Neuroscience, GPCR/G Protein
Bioactivity
PSB 0777 ammonium hydrate is a potent and selective adenosine A2A receptor full agonist, with K i values of 44.4 nM for rat A2A receptors and 360 nM for human A2A receptors. For rat and human A1 receptors, it has significantly lower affinity, with K i values of ≥10000 nM and 541 nM, respectively. The compound exhibits poor brain penetration and is not orally absorbable. It is of interest in research related to inflammatory bowel disease (IBD) [1] [2] [3].
Molecular Formula
C18H20N5O7S2.NH4.1.75H2O
Molecular Weight
532.09
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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