Donepezil-d4

• Description :

  Donepezil-d4 (E2020-d4 (free base) ) is deuterium labeled Donepezil. Donepezil (E2020 free base) is a specific and potent AChE inhibitor with IC50s of 8.12 nM and 11.6 nM for bovine AChE and human AChE, respectively[1].

• Product Name Alternative :

  E2020-d4 (free base)

• UNSPSC :

  12352005

• Target :

  Isotope-Labeled Compounds

• Related Pathways :

  Others

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Neurological Disease; Cancer

• Smiles :

  O=C1C2=CC(OC)=C(OC)C=C2CC1C([2H])([2H])C3CCN(CC3)C([2H])([2H])C4=CC=CC=C4

• Molecular Formula :

  C24H25D4NO3

• Molecular Weight :

  383.52

• References & Citations :

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Isotope-Labeled Compounds

• Clinical Information :

  No Development Reported

• CAS Number :

  [1219908-72-1]