Donepezil-d4

• Description:

  Donepezil-d4 (E2020-d4 (free base) ) is deuterium labeled Donepezil. Donepezil (E2020 free base) is a specific and potent AChE inhibitor with IC50s of 8.12 nM and 11.6 nM for bovine AChE and human AChE, respectively[1].

• Product Name Alternative:

  E2020-d4 (free base)

• UNSPSC:

  12352005

• Target:

  Isotope-Labeled Compounds

• Related Pathways:

  Others

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Neurological Disease; Cancer

• Smiles:

  O=C1C2=CC(OC)=C(OC)C=C2CC1C([2H])([2H])C3CCN(CC3)C([2H])([2H])C4=CC=CC=C4

• Molecular Formula:

  C24H25D4NO3

• Molecular Weight:

  383.52

• References & Citations:

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Isotope-Labeled Compounds

• Clinical Information:

  No Development Reported

• CAS Number:

  [1219908-72-1]