Donepezil N-oxide

Donepezil N-oxide

• CAS Number: 120013-84-5
• UNSPSC Description: Donepezil N-oxide, a metabolite of Donepezil (HY-14566), is human erythrocyte acetylcholinesterase (AChE) inhibitor[1].
• Target Antigen: Cholinesterase (ChE); Drug Metabolite
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease;Neuronal Signaling
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/donepezil-n-oxide.html
• Smiles: O=C1C(CC2CC[N+](CC3=CC=CC=C3)([O-])CC2)CC4=C1C=C(OC)C(OC)=C4
• Molecular Weight: 395.49
• References & Citations: [1]Francesca Groppa, et al. Monitoring Plasma Levels of Donepezil, 5-O-Desmethyl-Donepezil, 6-O-Desmethyl-Donepezil, and Donepezil-N-Oxide by a Novel HPLC Method in Patients With Alzheimer Disease. Ther Drug Monit. 2016 Feb;38(1):108-13.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported