Products for Research Use Only
RegisterLogin

(9R) -RO7185876

CAT: 0804-HY-145343A-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-145343A-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
(9R) -RO7185876 (Compound example 16) is a γ-secretase inhibitor. (9R) -RO7185876 inhibits Αβ42 secretion. (9R) -RO7185876 can be used for the researches of Alzheimer's disease, cerebral amyloid angiopathy, hereditary cerebral hemorrhage with amyloidosis, multi-infarct dementia, dementia pugilistica or Down syndrome[1].
CAS Number
2226077-86-5
UNSPSC
12352005
Target
Amyloid-β; γ-secretase
Related Pathways
Neuronal Signaling; Stem Cell/Wnt
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Purity
99.51
Smiles
FC(C(F)=C(C=C1)F)=C1[C@]2([H])C3=NC(N[C@H]4[C@@H]5CN(C6=NC=NC(C)=C6)C[C@H]4CC5)=NN3CCCC2
Molecular Formula
C25H28F3N7
Molecular Weight
483.53
References & Citations
[1]Bjoern Bartels, et al. Bicyclic heteroaryl derivatives. WO2018083050. WIPO. 2018-05-11.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-145343-01RO7185876
HY-13631N(9R) -Exatecan
HY-P2282-01APTSTAT3-9R
HY-P10116APTSTAT3-9R, scrambled
HY-154959A-01(9R,12aR) -AZD4747
HY-43565C(1S,9R) -Ac-Exatecan
HY-13631Q(1R,9R) -rel-Exatecan
HY-13631I-01(1S,9R) -Exatecan (mesylate)
HY-N12486A(3S,8R,9R) -Isofalcarintriol
HY-13631J-01(1R,9R) -Exatecan (mesylate)

Alternative Products

CatalogName
T204358-01(9R) -RO7185876
MBS5800128RO7185876
C8721-100ATS-9R
4058134.1000RVG-9R
TP2222APTSTAT3-9R
320213-01IL-9R
BSB46382-019R-Cobicistat
GTR19280871-01(9R) -Exatecan

Popular Products