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BMS-884775

CAT: 0804-HY-120612Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-120612Size:1 Each
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Description
BMS-884775 is a selective and orally active P2Y1 antagonist with an IC50 of 0.1 nM for the human P2Y1 receptor. BMS-884775 has a similar efficacy in preventing arterial thrombosis to Clopidogrel and Prasugrel (HY-15284), but treatment with BMS-884775 results in shorter bleeding time and lower bleeding risk. BMS-884775 can be used in research related to antiplatelet and arterial thrombosis-associated diseases[1][2].
CAS Number
1557206-59-3
UNSPSC
12352005
Target
P2Y Receptor
Related Pathways
GPCR/G Protein
Field of Research
Cardiovascular Disease
Smiles
O=C(NC1=NC2=CC=C(Cl)N=C2S1)NC3=CC=CC=C3N4CC5(CCN(CC(C)(C)C)CC5)C6=C4C(O)=CC(F)=C6C7=CC=C(F)C=C7
Molecular Formula
C36H35ClF2N6O2S
Molecular Weight
689.22
References & Citations
[1]Wong P, et al. Differential effects of P2Y1 versus P2Y12 receptor antagonism on thrombosis and bleeding in rabbits. European Heart Journal, 2013, 34 (suppl_1) : P1431.|[2]Tscharre M, et al. Novel Antiplatelet Agents in Cardiovascular Disease. J Cardiovasc Pharmacol Ther. 2020 May;25 (3) :191-200.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
P2Y1 Receptor

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