BMS 183920

• Description:

  BMS 183920 is a diacidic and potent angiotensin II receptor antagonist, with a Ki value of 2.9 nM in the rat adrenal cortex binding assay and a KB value of 0.061 nM in the rabbit aorta functional assay. BMS 183920 can be used for research of antihypertensive[1][2].

• UNSPSC:

  12352005

• Target:

  Angiotensin Receptor

• Related Pathways:

  GPCR/G Protein

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Cardiovascular Disease

• Smiles:

  O=C(C1=C(OC2=CC=C(C3=CC=CC=C3C4=NN=NN4)C=C2)C(C5CC5)=NC6=CC=CC=C16)O

• Molecular Formula:

  C26H19N5O3

• Molecular Weight:

  449.46

• References & Citations:

  [1]Obermeier MT, et al. Prodrugs of BMS-183920: metabolism and permeability considerations. J Pharm Sci. 1996 Aug;85 (8) :828-33.|[2]Wexler RR, et al. Nonpeptide angiotensin II receptor antagonists: the next generation in antihypertensive therapy. J Med Chem. 1996 Feb 2;39 (3) :625-56.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [153072-33-4]