Products for Research Use Only
RegisterLogin

BMS-187308

CAT: 0804-HY-117814Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-117814Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
BMS-187308 is an orally active endothelin-A (ETA) antagonist, with Kis of 4.7 nM for ETA and 1.7 μM for ETB. BMS-187308 inhibits the pressor response to ET-1 (ED25: 1.2 µmol/kg; iv) . BMS-187308 is a suitable tool for investigating the role of endothelin[1].
CAS Number
153624-15-8
UNSPSC
12352005
Target
Endothelin Receptor
Related Pathways
GPCR/G Protein
Field of Research
Cardiovascular Disease
Smiles
O=S(C1=CC=CC=C1C2=CC=C(CC(C)C)C=C2N)(NC3=C(C)C(C)=NO3)=O
Molecular Formula
C21H25N3O3S
Molecular Weight
399.51
References & Citations
[1]Murugesan N, et al. Biphenylsulfonamide endothelin antagonists: structure-activity relationships of a series of mono- and disubstituted analogues and pharmacology of the orally active endothelin antagonist 2'-amino-N- (3,4-dimethyl-5-isoxazolyl) -4'- (2-methylpropyl) [1, 1'-biphenyl]-2-sulfonamide (BMS-187308) . J Med Chem. 1998 Dec 17;41 (26) :5198-218.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
ETA; ETB

Related Products

CatalogName
HY-172736-01BMS-986458
HY-14225BMS-764459
HY-145373BMS-986143
HY-115874BMS-753426
HY-15352-01BMS 561390
HY-120625BMS-358233
HY-50883-01BMS 299897
HY-116274-01BMS-8
HY-19837-01BMS-986120
HY-11092-01BMS-509744

Alternative Products

CatalogName
GTR19195367-01BMS-187308
MBS386661-01BMS-806 (BMS 378806)
A11201-2BMS-806 (BMS 378806) 2mg
A11201-1BMS-806 (BMS 378806) 1mg
A11201-500BMS-806 (BMS 378806) 500mg
A11201-25BMS-806 (BMS 378806) 25mg
BA1866-5BMS-986094
BA9174-50BMS-564929
BA5455-5BMS-986278
BA5193-5BMS-986224

Popular Products