INU-101

CAT: 0804-HY-117428Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-117428Size:1 Each
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Description
INU-101 is a potent, selective and orally active 11β-hydroxysteroid dehydrogenase (11β-HSD) type 1 inhibitor. INU-101 has highly potent inhibitory activity in mouse, monkey and human 11β-HSD1, derived from liver microsomes. INU-101 can enhance insulin sensitivity and lower the fasting blood glucose level. INU-101 can be used for the research of metabolic disease, such as diabetes[1].
CAS Number
[1513828-41-5]
UNSPSC
12352005
Target
11β-HSD
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Metabolic Disease
Smiles
NC([C@]12C[C@@H](C3)C(NC(C(C)(C)NS(=O)(C4=C(C=CC=C4)F)=O)=O)[C@@H](C[C@@H]3C2)C1)=O
Molecular Formula
C21H28FN3O4S
Molecular Weight
437.53
References & Citations
[1]Hong SP, et al. A novel highly potent and selective 11β-hydroxysteroid dehydrogenase type 1 inhibitor, INU-101. Eur J Pharmacol. 2018 Sep 15;835:169-178.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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