CUMI-101

• Description :

  CUMI-101 (compound 8) is a 5-HT1AR agonist (Ki=0.15 nM) with an EC50 of 0.1 nM in the [35S]GTPγS binding assay. CUMI-101 can be used in the research of neurological diseases[1].

• UNSPSC :

  12352005

• Target :

  5-HT Receptor

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/cumi-101.html

• Smiles :

  O=C(N(N=CC1=O)CCCCN2CCN(CC2)C3=CC=CC=C3OC)N1C

• Molecular Formula :

  C19H27N5O3

• Molecular Weight :

  373.45

• References & Citations :

  [1]Kumar J S D, et al. Synthesis and evaluation of arylpiperazines derivatives of 3, 5-dioxo- (2H, 4H) -1, 2, 4-triazine as 5-HT1AR ligands[J]. Bioorganic & medicinal chemistry letters, 2014, 24 (19) : 4759-4762.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [179756-61-7]