MAL3-101

• UNSPSC Description:

  MAL3-101 is a potent HSP70 allosteric inhibitor. MAL3-101 inhibits HSP70 ATPase activity by blocking Hsp40 co-chaperone interaction. MAL3-101 can be used for researching muscle invasive bladder cancer (MIBC)[1].

• Target Antigen:

  HSP

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage;Metabolic Enzyme/Protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/mal3-101.html

• Purity:

  98.22

• Solubility:

  DMSO : 50 mg/mL (ultrasonic)

• Smiles:

  CC(N(C(NC1C2=CC=C(C3=CC=CC=C3)C=C2)=O)CCCCCC(N(CCCCCC)C(C(NCCCC)=O)C4=CC=C(C(C(OC)=O)=C4)OCC(OC)=O)=O)=C1C(OCC5=CC=CC=C5)=O

• Molecular Weight:

  931.12

• References & Citations:

  [1]Prince T, et al. Dual targeting of HSP70 does not induce the heat shock response and synergistically reduces cell viability in muscle invasive bladder cancer. Oncotarget. 2018 Aug 24;9(66):32702-32717.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  831217-40-4