UCPH-101

CAT: 0804-HY-10914-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-10914-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
UCPH-101 is an excitatory amino acid transporter subtype 1 (EAAT1) inhibitor with an IC50 of 0.66 μM.
CAS Number
[1118460-77-7]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
EAAT
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/UCPH-101.html
Purity
98.61
Solubility
DMSO : ≥ 50 mg/mL
Smiles
O=C(C1)C2=C(OC(N)=C(C#N)C2C3=CC=C(OC)C=C3)CC1C4=CC=CC5=C4C=CC=C5
Molecular Formula
C27H22N2O3
Molecular Weight
422.48
Precautions
H302, H315, H319, H335
References & Citations
[1]Abrahamsen B, et al. Allosteric modulation of an excitatory amino acid transporter: the subtype-selective inhibitor UCPH-101 exerts sustained inhibition of EAAT1 through an intramonomeric site in the trimerization domain. J Neurosci. 2013 Jan 16;33 (3) :1068-87.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
EAAT1

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