U 93385

CAT: 0804-HY-106928Size: 1 EachDry Ice: NoHazardous: No

CAT#:0804-HY-106928Size:1 Each

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Description

U93385 is a 5-HT₁A receptor agonist. U93385 exhibits no significant α₂ adrenergic, D₂ dopamine, or other receptor activities. U93385 has a heart rate regulating effect, stimulating the vagus nerve to induce bradycardia. U93385 can be used to study the 5-HT₁A receptor-mediated vagal nerve tolerance mechanism[1].

CAS Number

[147145-16-2]

UNSPSC

12352005

Target

5-HT Receptor

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Neurological Disease

Smiles

NC(C1=C2[C@@]3([H])[C@](CCC2=CC=C1)([H])N(CCC)CC3)=O

Molecular Formula

C16H22N2O

Molecular Weight

258.36

References & Citations

[1]McCall RB, et al. Rapid and long duration tolerance to the vagal bradycardic effects of 5-HT1A receptor agonists. Behav Brain Res. 1996;73 (1-2) :297-300.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Phase 1

Isoform

5-HT1 Receptor

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U 93385

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