BMS 275183

CAT: 0804-HY-106219Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-106219Size:1 Each
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
BMS 275183 is a potent, orally active analogue of Paclitaxel (HY-B0015) . BMS 275183 can stabilize microtubules and exhibits antitumor activity in in vivo tumor models. BMS 275183 is active in vitro against Paclitaxel-resistant tumors including those harboring tubulin mutations or overexpressing P-glycoprotein. BMS 275183 can be used for cancer research, such as non-small cell lung cancer (NSCLC) and prostate carcinoma[1].
CAS Number
[355113-98-3]
UNSPSC
12352005
Target
Microtubule/Tubulin; P-glycoprotein
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton; Membrane Transporter/Ion Channel
Field of Research
Cancer
Smiles
COC(O[C@]12[C@@]([C@]3([C@@H](O)C[C@@]1([H])OC2)C)([H])[C@@H]([C@]4(C(C)(C([C@@H](OC(C)=O)C3=O)=C(C)[C@@H](OC([C@H](O)[C@H](C(C)(C)C)NC(OC(C)(C)C)=O)=O)C4)C)O)OC(C5=CC=CC=C5)=O)=O
Molecular Formula
C43H59NO16
Molecular Weight
845.93
References & Citations
[1]Bröker LE, et al. Phase I trial with BMS-275183, a novel oral taxane with promising antitumor activity. Clin Cancer Res. 2006 Mar 15;12 (6) :1760-7.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2

Related Products

CatalogName
HY-139562BMS-986318
HY-108432BMS-741672
HY-P2021BMS 180742
HY-19667BMS-561392
HY-120625BMS-358233
HY-15352-01BMS 561390
HY-115874BMS-753426
HY-145373BMS-986143
HY-14225BMS-764459
HY-116033-01BMS-363131

Alternative Products

CatalogName

Popular Products