MDL 43291

• Description :

  MDL 43291 is a competitive leukotriene (LT) receptor antagonist. MDL 43291 antagonize LTD4 and LTE4 with pA2 of 6.7. MDL 43291 does not antagonize histamine, carbachol or substance P. MDL 43291 can be used for the researches of inflammation and immunology, such as asthma[1].

• UNSPSC :

  12352005

• Target :

  Leukotriene Receptor

• Related Pathways :

  GPCR/G Protein

• Field of Research :

  Inflammation/Immunology

• Smiles :

  OC(CS[C@H]1[C@@](O2)([H])[C@](CCC2=O)([H])CC/C1=C/CCCCCCCCCCCCC)=O

• Molecular Formula :

  C25H42O4S

• Molecular Weight :

  438.66

• References & Citations :

  [1]Gieske TH, et al. Conformationally restricted leukotriene receptor antagonists: [ (octahydro-2-oxo-7-tetradecylidene-2H-1-benzopyran-8-yl) thio]ace tic acids. Pharmacology. 1990;40 (5) :271-6.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  LTD4/CysLT1; LTE4

• CAS Number :

  [129357-91-1]