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PKR activator 3

CAT: 0804-HY-19702-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-19702-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PKR activator 3 is a pyruvate kinase isoform PKR activator extracted from patent WO2014139144A1, compound 160. PKR activator 3 can be used for the research of PKR function related diseases, including cancer, diabetes, obesity, autoimmune disorders, and benign prostatic hyperplasia[1].
CAS Number
1628428-01-2
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Pyruvate Kinase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Cancer; Metabolic Disease; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/pkr-activator-3.html
Purity
99.82
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
N1C2C(=C(S(NC3=CC=C(C(N4CCC(O)(CC(C)C)CC4)=O)C=C3)(=O)=O)C=CC=2)N=CC=1
Molecular Formula
C24H28N4O4S
Molecular Weight
468.57
Precautions
H302, H315, H319, H335
References & Citations
[1]Popovici-Muller, et al. Preparation of N- (piperidinecarbonylphenyl) sulfonamide compounds as pyruvate kinase modulators. From PCT Int. Appl. (2014), WO2014139144A1 20140918.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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