PKR-IN-1

• Description:

  PKR-IN-1 (Compound 5s) is a pyruvate kinase (PK) inhibitor that has antifungal activity, with an EC50 of 0.21 μg/mL for R. solani[1].

• UNSPSC:

  12352005

• Target:

  Fungal; Pyruvate Kinase

• Related Pathways:

  Anti-infection; Metabolic Enzyme/Protease

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Smiles:

  ClC1=NSC(C2=CSC(C3=NN=C(C(Cl)(Cl)Cl)O3)=N2)=C1Cl

• Molecular Formula:

  C9HCl5N4OS2

• Molecular Weight:

  422.53

• References & Citations:

  [1]Gao W, et al. Pyruvate Kinase-Based Novel 2-Thiazol-2-yl-1,3,4-oxadiazoles Discovery as Fungicidal Highly Active Leads. J Agric Food Chem. 2025 Jan 15;73 (2) :1075-1085.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [3057531-75-3]