Ir-CA

CAT: 0931-T86741-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0931-T86741-01Size:10 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2870682-93-0

Target

Apoptosis, Autophagy

Related Pathways

Apoptosis, Autophagy

Bioactivity

Ir-CA is an antitumor agent that accumulates in mitochondria, inducing mitochondrial dysfunction, apoptosis, and autophagy. It initiates mitophagy and cell cycle arrest to kill Cisplatin-resistant A549R cells and effectively inhibits metastasis by inhibiting MMP-2/MMP-9 [1].

Smiles

[P+5]([F-])([F-])([F-])([F-])([F-])[F-].C(NC(/C=C/C1=CC=CC=C1)=O)C=2C=C3[N]([Ir+3]45([N]=6C3=CC(C)=CC6)([C-]=7C(C=8[N]4=CC=CC8)=CC=CC7)[C-]=9C(C=%10[N]5=CC=CC%10)=CC=CC9)=CC2

Molecular Formula

C43H35F6IrN5OP

Molecular Weight

974.95

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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