IR-58

• Target:

  Others|||Apoptosis|||Autophagy

• Related Pathways:

  Others|||Apoptosis|||Autophagy

• Bioactivity:

  IR-58 is a mitochondria-targeting near-infrared (NIR) fluorophore that serves as an autophagy enhancer. It eliminates tumor cells and triggers apoptosis by promoting excessive autophagy through the reactive oxygen species (ROS) -Akt-mTOR pathway [1].

• Smiles:

  C(CCCCCCCCCC(NCC(OC)=O)=O)N1C=2C(C(C)(C)C1=CC=C3C(Cl)=C(C=CC4=[N+](CCCCCCCCCCC(NCC(OC)=O)=O)C=5C(C4(C)C)=CC=CC5)CCC3)=CC=CC2.[Br-]

• Molecular Formula:

  C58H82BrClN4O6

• Molecular Weight:

  1046.65

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2374274-85-6