IR-990

• Description:

  IR-990 is an activatable NIR-II fluorescent probe with an acceptor-π-acceptor (A-π-A) skeleton for real-time detection of H2O2 in vivo. IR-990 is a powerful diagnosis of agent-induced liver injury (DILI) [1].

• UNSPSC:

  12171500

• Target:

  Fluorescent Dye

• Type:

  Dye Reagents

• Related Pathways:

  Others

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/ir-990.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC1 (C) OB (C2=CC=C (COC (C=CC (/C=C/C3=[N+] (C4=CC=CC5=C4C3=CC=C5) CC) =C6) =C6/C=C/C7=[N+] (C8=C9C7=CC=CC9=CC=C8) CC) C=C2) OC1 (C) C.[I-].[I-]

• Molecular Formula:

  C49H47BI2N2O3

• Molecular Weight:

  976.53

• References & Citations:

  [1]Yang Tian, et al. H2O2-Activated NIR-II Fluorescent Probe with a Large Stokes Shift for High-Contrast Imaging in Drug-Induced Liver Injury Mice. Anal Chem. 2022 Aug 16;94 (32) :11321-11328.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Dye Reagents

• Clinical Information:

  No Development Reported