IR-990

• Description :

  IR-990 is an activatable NIR-II fluorescent probe with an acceptor-π-acceptor (A-π-A) skeleton for real-time detection of H2O2 in vivo. IR-990 is a powerful diagnosis of agent-induced liver injury (DILI) [1].

• UNSPSC :

  12171500

• Target :

  Fluorescent Dye

• Type :

  Dye Reagents

• Related Pathways :

  Others

• Field of Research :

  Others

• Assay Protocol :

  https://www.medchemexpress.com/ir-990.html

• Solubility :

  10 mM in DMSO

• Smiles :

  CC1(C)OB(C2=CC=C(COC(C=CC(/C=C/C3=[N+](C4=CC=CC5=C4C3=CC=C5)CC)=C6)=C6/C=C/C7=[N+](C8=C9C7=CC=CC9=CC=C8)CC)C=C2)OC1(C)C.[I-].[I-]

• Molecular Formula :

  C49H47BI2N2O3

• Molecular Weight :

  976.53

• References & Citations :

  [1]Yang Tian, et al. H2O2-Activated NIR-II Fluorescent Probe with a Large Stokes Shift for High-Contrast Imaging in Drug-Induced Liver Injury Mice. Anal Chem. 2022 Aug 16;94 (32) :11321-11328.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Dye Reagents

• Clinical Information :

  No Development Reported