IR-Crizotinib

CAT: 0931-T82049-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0931-T82049-01Size:5 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
CAS Number
2387927-74-2
Target
NF-?B
Related Pathways
NF-?B
Bioactivity
IR-Crizotinib is a conjugate of the near-infrared dye IR-786 and Crizotinib, an NF-?B-inducing kinase (NIK) inhibitor, with an IC50 of 3.381 ?M for intracranial glioblastoma (GBM) localization in mice. It has the ability to cross the blood-brain barrier and fluorescently mark GBM, and demonstrates efficacy in inhibiting glioma proliferation and invasion both in vitro and in vivo, making it significant in cancer research [1].
Smiles
C(\C=C\1/C(C)(C)C=2C(N1C)=CC=CC2)=C\3C(=C(/C=C/C=4C(C)(C)C=5C([N+]4C)=CC=CC5)CCC3)N6CCC(CC6)N7C=C(C=N7)C=8C=C(O[C@H](C)C9=C(Cl)C(F)=CC=C9Cl)C(N)=NC8.[I-]
Molecular Formula
C53H57Cl2FIN7O
Molecular Weight
1024.88
Shipping Conditions
Cool pack
Storage Temperature
-20°C

Related Products

CatalogName
T1661-01Crizotinib
T8399-01Crizotinib hydrochloride
T1661L-01Crizotinib acetate
T6357-01(S) -crizotinib
TMIJ-0115-01Crizotinib-d5
T19510-012-Keto Crizotinib
T31097-01Crizotinib Interm 7654
TYD-03677-01Crizotinib Impurity 23
T82052-01IR-990
T79284-01IR-251

Alternative Products

CatalogName
MBS5823701IR-Crizotinib
M16370-01Crizotinib
RM-C182606-01(S) -Crizotinib
MBS578906(S)-crizotinib
C10790-01Crizotinib hydrochloride
A3020-100(R)-Crizotinib
HY-50878S1Crizotinib-d8
007107Crizotinib discontinued

Popular Products