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Cbl-b-IN-6

CAT: 0931-T79893-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T79893-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2815221-33-9
Target
E1/E2/E3 Enzyme
Related Pathways
Ubiquitination
Bioactivity
Cbl-b-IN-6 (Compound 246) is an inhibitor of casitas B-lineage lymphoma-b (Cbl-b) and c-Cbl, with half-maximal inhibitory concentrations (IC50s) of 6.7 nM for Cbl-b and 5.2 nM for c-Cbl, respectively [1].
Smiles
C(C1(CC(F)(F)C1)C2=CC(=CC=C2)N3CC=4C(C3=O)=CC([C@@H](NC5(C)CCC5)C)=CC4C(F)(F)F)C=6N(C)C=NN6
Molecular Formula
C30H32F5N5O
Molecular Weight
573.6
Shipping Conditions
Ice Packs
Storage Temperature
-20°C