Cbl-b-IN-7

• Target:

  E1/E2/E3 Enzyme

• Related Pathways:

  Ubiquitination

• Bioactivity:

  Cbl-b-IN-7 (Compound 248) is an inhibitor of casitas B-lineage lymphoma-b (Cbl-b) and c-Cbl, with half-maximal inhibitory concentrations (IC50s) of 6.7 nM and 5.2 nM, respectively [1].

• Smiles:

  [C@@H](F)(C1(COC1)C2=CC(=CC=C2)N3CC=4C(C3=O)=CC([C@@H](NC5(C)CCC5)C)=CC4C(F)(F)F)C=6N(C)C=NN6

• Molecular Formula:

  C29H31F4N5O2

• Molecular Weight:

  557.58

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2815221-35-1