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Cbl-b-IN-15

CAT:
931-T208287-01
Size:
10 mg
Price:
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  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
Cbl-b-IN-15 - image 1

Cbl-b-IN-15

  • Target:

    E1/E2/E3 Enzyme

  • Related Pathways:

    Ubiquitination

  • Bioactivity:

    Cbl-b-IN-15 (compound 25) is an inhibitor of the RING finger E3 ubiquitin ligase Cbl, demonstrating an IC50 of 15 nM. Cbl-b refers to Casitas B-lineage Lymphoma proto-oncogene-b, which can inhibit the activation of T cells, natural killer (NK) cells, and B cells. Cbl-b-IN-15 can activate T cell function with an EC50 of 0.41 ?M.

  • Molecular Formula:

    C27H27N5O3

  • Shipping Conditions:

    Cool pack

  • Storage Temperature:

    -20°C

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