Cbl-b-IN-13

• Target:

  E1/E2/E3 Enzyme

• Related Pathways:

  Ubiquitination

• Bioactivity:

  Cbl-b-IN-13 (Example 520) is a potent Cbl-b inhibitor with an IC50 of less than 100 nM, capable of activating T-cells [1].

• Smiles:

  O=C1C2=CC(=CC(=C2CN1C3=CC=CC(=C3)C4(COC4)CC5=NN=CN5C)C(F)(F)F)CN6CCC7(C6)CC7

• Molecular Formula:

  C29H30F3N5O2

• Molecular Weight:

  537.58

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2368841-85-2