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Cbl-b-IN-16

CAT:
931-T209172-01
Size:
10 mg
Price:
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  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
Cbl-b-IN-16 - image 1

Cbl-b-IN-16

  • Target:

    E1/E2/E3 Enzyme

  • Related Pathways:

    Ubiquitination

  • Bioactivity:

    Cbl-b-IN-16 (compound 31) is an orally active inhibitor of the RING E3 ligase Cbl-b, with an IC50 of 30 nM. It enhances IL-2 production in human T cells with an EC50 of 230 nM and exhibits antitumor activity.

  • Molecular Formula:

    C26H27F3N6O

  • Shipping Conditions:

    Cool pack

  • Storage Temperature:

    -20°C

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