Cbl-b-IN-16

CAT: 0931-MF-0116645-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0116645-01Size:10 mg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
E1/E2/E3 Enzyme
Related Pathways
Ubiquitination
Bioactivity
Cbl-b-IN-16 (compound 31) is an orally active inhibitor of the RING E3 ligase Cbl-b, with an IC50 of 30 nM. It enhances IL-2 production in human T cells with an EC50 of 230 nM and exhibits antitumor activity.
Molecular Formula
C26H27F3N6O
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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