HDAC-IN-62

• Target:

  HDAC|||Autophagy

• Related Pathways:

  DNA Damage/DNA Repair|||Chromatin/Epigenetic|||Autophagy

• Bioactivity:

  HDAC-IN-62 (Compound 5), an HDAC inhibitor, exhibits IC50 values of 0.78, 1.0, and 1.2 ?M for HDAC6, HDAC8, and HDAC11, respectively. This compound suppresses microglial activation via autophagy induction and reduces nitric oxide production, demonstrating anti-inflammatory and antidepressant properties. Additionally, HDAC-IN-62 has been shown to inhibit microglial activation in mouse brains [1].

• Molecular Formula:

  C15H14N2O3S

• Molecular Weight:

  302.35

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C