HDAC-IN-62

CAT: 0931-MF-0157191-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0157191-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
HDAC|||Autophagy
Related Pathways
DNA Damage/DNA Repair|||Chromatin/Epigenetic|||Autophagy
Bioactivity
HDAC-IN-62 (Compound 5), an HDAC inhibitor, exhibits IC50 values of 0.78, 1.0, and 1.2 ?M for HDAC6, HDAC8, and HDAC11, respectively. This compound suppresses microglial activation via autophagy induction and reduces nitric oxide production, demonstrating anti-inflammatory and antidepressant properties. Additionally, HDAC-IN-62 has been shown to inhibit microglial activation in mouse brains [1].
Molecular Formula
C15H14N2O3S
Molecular Weight
302.35
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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