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PROTAC AR Degrader-5

CAT: 0931-T87255-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T87255-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2703021-51-4
Target
Androgen Receptor, PROTACs
Related Pathways
PROTAC, Endocrinology/Hormones
Bioactivity
PROTAC AR Degrader-5 (compound A46) is a powerful AR PROTAC Degrader exhibiting an IC 50 of 49 nM. It not only inhibits sebaceous plaque but also promotes hair regeneration [1].
Smiles
S=C1N(C(=O)C(C)(C)N1C=2C=CC(=NC2)C3=CC=C(OCCCCOCC(N[C@H](C(=O)N4[C@H](C(NCC5=CC=C(C=C5)C6=C(C)N=CS6)=O)C[C@@H](O)C4)C(C)(C)C)=O)C=C3)C7=C(F)C(C(F)(F)F)=C(C#N)C=C7
Molecular Formula
C52H54F4N8O7S2
Molecular Weight
1043.16
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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