DPP-4-IN-8

CAT: 0931-MF-0157103-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0157103-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Others|||Proteasome|||Interleukin|||TNF
Related Pathways
Proteases/Proteasome|||Apoptosis|||Immunology/Inflammation|||Others|||Ubiquitination
Bioactivity
DPP-4-IN-8 (compound 27) is a potent and selective inhibitor of dipeptidyl peptidase 4 (DPP4), with an inhibition constant (Ki) of 0.96 ?M. It inhibits the dipeptidase activity of DPP4 in both Caco-2 and HepG-2 cells and dose-dependently reduces the expression of chemokines such as tumor necrosis factor-? (TNF-?), interleukin-6 (IL-6), and interleukin-1? (IL-1?) [1].
Molecular Formula
C16H12ClNO6
Molecular Weight
349.72
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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