DPP-4-IN-12

DPP-4-IN-12

• UNSPSC Description: DPP-4-IN-12 (compound 46) is a potent DPP-4 inhibitor with IC50 value of 2 nM. DPP-4-IN-12 can be used in the study of type 2 diabetes[1].
• Target Antigen: Dipeptidyl Peptidase
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Field of Research: Metabolic Disease
• Assay Protocol: https://www.medchemexpress.com/dpp-4-in-12.html
• Smiles: CC1=C(C(N=C(N1C(CN2CC3=CN(S(=O)(C)=O)N=C3C2)=O)N)C4=CC(F)=C(C=C4)F)C(O)=O
• Molecular Weight: 494.47
• References & Citations: [1]Mobeen B, et al. Discovery of the selective and nanomolar inhibitor of DPP-4 more potent than sitagliptin by structure-guided rational design. Eur J Med Chem. 2024 Sep 5;279:116834.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported