DPP-4-IN-3

DPP-4-IN-3

• CAS Number: 2402735-14-0
• UNSPSC Description: DPP-4-IN-3 (Compound 5a) is a potent dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC50 of 0.75 nM. DPP-4-IN-3 shows excellent antioxidant and insulinotropic activity[1].
• Target Antigen: Dipeptidyl Peptidase; Reactive Oxygen Species
• Type: Reference compound
• Related Pathways: Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB
• Applications: Metabolism-protein/nucleotide metabolism
• Field of Research: Metabolic Disease
• Assay Protocol: https://www.medchemexpress.com/dpp-4-in-3.html
• Solubility: 10 mM in DMSO
• Smiles: CCOC(N1CCN(CC1)C2=NN3C(C=C2)=NN=C3C4=CC=CC(C)=C4)=O
• Molecular Weight: 366.42
• References & Citations: [1]Bindu B, et al. Synthesis and discovery of triazolo-pyridazine-6-yl-substituted piperazines as effective anti-diabetic drugs; evaluated over dipeptidyl peptidase-4 inhibition mechanism and insulinotropic activities. Eur J Med Chem. 2020 Feb 1;187:111912.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported