DPP-4-IN-18

CAT: 0804-HY-Z1764Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-Z1764Size:1 Each
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
DPP-4-IN-18 (Sitagliptin impurity 3) (Compound 4) impurity 3 is a potent, selective and orally active DPP-4 inhibitor with an IC50 of 27 nM. DPP-4-IN-18 can effectively prevent DPP-4 from degrading glucagon-like peptide 1 (GLP-1), thereby increasing the level of active GLP-1. DPP-4-IN-18 can be used for the research of type 2 diabetes[1].
CAS Number
[486460-31-5]
Product Name Alternative
Sitagliptin impurity 3
UNSPSC
12352005
Hazard Statement
H319-H373
Target
Dipeptidyl Peptidase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Metabolic Disease
Smiles
O=C(N1CC2=NN=C(C(F)(F)F)N2CC1)C[C@H](N)CC3=CC(F)=CC=C3F
Molecular Formula
C16H16F5N5O
Molecular Weight
389.32
Precautions
P260-P264-P280-P305+P351+P338-P501
References & Citations
[1]Thornberry NA, et al. Discovery of JANUVIA (Sitagliptin), a selective dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes. Curr Top Med Chem. 2007;7 (6) :557-68.
Shipping Conditions
Room temperature
Scientific Category
Reference compound2
Clinical Information
No Development Reported
Isoform
DPP-4

Related Products

CatalogName
HY-146455DPP-4-IN-3
HY-151384DPP-4-IN-2
HY-162513DPP-4-IN-10
HY-170800DPP-4-IN-15
HY-169110DPP-4-IN-12
HY-155027DPP-4-IN-8
HY-151383DPP-4-IN-1
HY-157390DPP-4-IN-9
HY-159491DPP-4-IN-11
HY-168621DPP-4-IN-13

Alternative Products

CatalogName
T86303-01DPP-4-IN-9
T89089-01DPP-4-IN-11
T201436-01DPP-4-IN-13
T61018-01DPP-4-IN-2
T211072-01DPP-4-IN-16
T24016-01DPP-4-PIOL
T200529-01DPP-4-IN-12
T88111-01DPP-4-IN-10
T204855-01DPP-4-IN-14
T205036-01DPP-4-IN-15

Popular Products