DPP-4-IN-2

• Description:

  DPP-4-IN-2 (compound b2) is a potent DPP-4 (dipeptidyl peptidase 4) inhibitor, with an IC50of 79 nM. DPP-4-IN-2 is a structurally analogs of Alogliptin (HY-A0023A) . DPP-4-IN-2 can be used for diabetes research[1].

• UNSPSC:

  12352005

• Target:

  Dipeptidyl Peptidase

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/dpp-4-in-2.html

• Solubility:

  10 mM in DMSO

• Smiles:

  N#CC1=CC=CC=C1CN (C (N2CCNCC2) =C3) C4=CC=NN4C3=O

• Molecular Formula:

  C18H18N6O

• Molecular Weight:

  334.38

• References & Citations:

  [1]Shen J, et al. Structural optimization of pyrazolo[1,5-a]pyrimidine derivatives as potent and highly selective DPP-4 inhibitors. Eur J Med Chem. 2020 Dec 15;208:112850.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  DPP-4

• CAS Number:

  2133900-95-3