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DPP-4-IN-17

CAT: 0931-T212193-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T212193-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Proteasome
Related Pathways
Ubiquitination, Proteases/Proteasome
Bioactivity
DPP-4-IN-17 is an orally active and selective inhibitor of dipeptidyl peptidase-4 (DPP-4) with an IC50 value of 0.12 nM. It increases the enzyme's Km value (75.73 μM compared to the substrate alone at 27.18 μM) and reduces catalytic efficiency. In Streptozotocin (STZ) /Nicotinamide (NA) -induced diabetic rats, DPP-4-IN-17 lowers blood glucose levels and reverses weight loss. This compound is useful for research in type 2 diabetes (T2DM) .
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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