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Antitumor agent-101

CAT: 0931-T79249-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T79249-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2848632-52-8
Target
Histone Methyltransferase, Glucagon Receptor
Related Pathways
GPCR/G Protein, Chromatin/Epigenetic
Bioactivity
Antitumor agent-101 is a selective, covalent inhibitor targeting lysine methyltransferases G9a/GLP, demonstrating IC50 values of 8.5 nM for G9a and 5.5 nM for GLP. It exhibits antitumor efficacy in the PANC-1 xenograft model [1].
Smiles
N(C=1C2=C(C=C(OCCCN3CCCC3)C(OC)=C2)N=C(N(C(C=C)=O)C)N1)C4CCN(C)CC4
Molecular Formula
C26H38N6O3
Molecular Weight
482.62
Shipping Conditions
Ice Packs
Storage Temperature
-20°C