Antitumor agent-101

• Target:

  Histone Methyltransferase|||Glucagon Receptor

• Related Pathways:

  GPCR/G Protein|||Chromatin/Epigenetic

• Bioactivity:

  Antitumor agent-101 is a selective, covalent inhibitor targeting lysine methyltransferases G9a/GLP, demonstrating IC50 values of 8.5 nM for G9a and 5.5 nM for GLP. It exhibits antitumor efficacy in the PANC-1 xenograft model [1].

• Smiles:

  N(C=1C2=C(C=C(OCCCN3CCCC3)C(OC)=C2)N=C(N(C(C=C)=O)C)N1)C4CCN(C)CC4

• Molecular Formula:

  C26H38N6O3

• Molecular Weight:

  482.62

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2848632-52-8