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SA09-Cu

CAT: 0931-T78987-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T78987-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
155641-16-0
Target
Others, Antibacterial
Related Pathways
Others, Microbiology/Virology
Bioactivity
SA09-Cu is a potent, noncompetitive inhibitor of NDM-1, with an IC50 of 9.6 nM. It inactivates NDM-1 by oxidizing the enzyme's Zn (II) -thiolate site and resists reduction by bacterial intracellular thiols. SA09-Cu effectively restores Meropenem efficacy against various clinical NDM-1-producing carbapenem-resistant Enterobacteriaceae (CRE) and hampers the progression of carbapenem resistance [1].
Smiles
N(CCO)(C)C=1[S-][Cu+2]2([S-]C(N(CCO)C)=[S]2)[S]1
Molecular Formula
C8H16CuN2O2S4
Molecular Weight
364.03
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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