CU-115

• Target:

  TLR

• Related Pathways:

  Immunology/Inflammation

• Purity:

  >99.99%

• Bioactivity:

  CU-115 is a selective and potent TLR8 antagonist with IC50 of 1.04 µM and =>50 µM for TLR8 and TLR7, respectively. CU-115 decreases production of TNF-? and IL-1? activated by R-848 in THP-1 cells.

• Smiles:

  Fc1cccc(I)c1C(=O)Nc1ccc(Oc2cc(cc(c2)C(F)(F)F)C(F)(F)F)cc1

• Molecular Formula:

  C21H11F7INO2

• Molecular Weight:

  569.21

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2471982-20-2