CU-115

• Target :

  TLR

• Related Pathways :

  Immunology/Inflammation

• Purity :

  >99.99%

• Bioactivity :

  CU-115 is a selective and potent TLR8 antagonist with IC50 of 1.04 µM and =>50 µM for TLR8 and TLR7, respectively. CU-115 decreases production of TNF-? and IL-1? activated by R-848 in THP-1 cells.

• Smiles :

  Fc1cccc(I)c1C(=O)Nc1ccc(Oc2cc(cc(c2)C(F)(F)F)C(F)(F)F)cc1

• Molecular Formula :

  C21H11F7INO2

• Molecular Weight :

  569.21

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2471982-20-2