CU-76

CAT: 0931-MF-0152546Size: 5 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0152546Size:5 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
CAS Number
2400954-58-5
Target
CGAS|||Others
Related Pathways
Immunology/Inflammation|||Others
Bioactivity
CU-76 is an inhibitor of cyclic GMP-AMP synthase (cGAS; IC50= 0.24 ?M) .1It reduces DNA-, but not Sendai virus-, induced dimerization of IFN regulatory factor 3 in THP-1 cells, indicating selectivity for the cGAS DNA sensing pathway over the RIG-I-MAVS RNA sensing pathway. CU-76 decreases IFN-stimulatory DNA-induced production of IFN-? in THP-1 cells when used at concentrations of 10, 30, and 100 ?M.
Smiles
N(C=1N=C(C(OC)=O)N=C(N)N1)C2=CC(F)=C(I)C(F)=C2
Molecular Formula
C11H8F2IN5O2
Molecular Weight
407.11
Shipping Conditions
Cool pack
Storage Temperature
-20°C

Related Products

CatalogName
MF-0041223-01CU-3
MF-0096933-01CU-32
MF-0015715-01CU-115
MF-0094414-01CU-CPT9b
MF-0021996-01CU-CPT17e
MF-0112359-01FA4-Cu
MF-0156967-01SA09-Cu
MF-0032649-01CU-CPT22
MF-0044499-01CU-CPD107
MF-0145753-01CU-2010

Alternative Products

CatalogName
MBS5799006CU-76
S8060-11BSuperoxide Dismutase, Cu (SOD Cu)
sc-51698SLP-76 (SLP-76/03)
MBS3844598-01CU-CPT22
MBS3613613-01CU-CPT17e
MBS3602788-01CU-3
HY-112051-01CU-CPT9b
BA6310-5.1CU-115
010-29CU-NP
BUP12011-01CU-CPD107

Popular Products