CU-CPT9b

• Target:

  TLR

• Related Pathways:

  Immunology/Inflammation

• Purity:

  0.981

• Bioactivity:

  CU-CPT9b (TLR8-specific antagonist 1) is an antagonist of toll-like receptor 8 (TLR8; Kd = 21 nM) . It inhibits activation of NF- B induced by the TLR8 agonist R-848 in TLR8-overexpressing HEK-Blue cells with an IC50 value of 0.7 nM.

• Smiles:

  Cc1cc(ccc1O)-c1ccnc2cc(O)ccc12

• Molecular Formula:

  C16H13NO2

• Molecular Weight:

  251.28

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2162962-69-6